Medical University of Warsaw:
1: Bobrowicz M, Kubacz M, Slusarczyk A, Winiarska M. CD37 in B Cell Derived
Tumors-More than Just a Docking Point for Monoclonal Antibodies. Int J Mol Sci.
2020 Dec 15;21(24):9531. doi: 10.3390/ijms21249531. PMID: 33333768; PMCID:
PMC7765243.
2: Lachota M, Vincenti M, Winiarska M, Boye K, Zagożdżon R, Malmberg KJ.
Prospects for NK Cell Therapy of Sarcoma. Cancers (Basel). 2020 Dec
11;12(12):3719. doi: 10.3390/cancers12123719. PMID: 33322371; PMCID: PMC7763692.
3: Domagala J, Lachota M, Klopotowska M, Graczyk-Jarzynka A, Domagala A, Zhylko
A, Soroczynska K, Winiarska M. The Tumor Microenvironment-A Metabolic Obstacle
to NK Cells' Activity. Cancers (Basel). 2020 Nov 27;12(12):3542. doi:
10.3390/cancers12123542. PMID: 33260925; PMCID: PMC7761432.
4: Komorowski L, Fidyt K, Patkowska E, Firczuk M. Philadelphia Chromosome-
Positive Leukemia in the Lymphoid Lineage-Similarities and Differences with the
Myeloid Lineage and Specific Vulnerabilities. Int J Mol Sci. 2020 Aug
12;21(16):5776. doi: 10.3390/ijms21165776. PMID: 32806528; PMCID: PMC7460962.
5: Zhylko A, Winiarska M, Graczyk-Jarzynka A. The Great War of Today:
Modifications of CAR-T Cells to Effectively Combat Malignancies. Cancers
(Basel). 2020 Jul 24;12(8):2030. doi: 10.3390/cancers12082030. PMID: 32722109;
PMCID: PMC7466082.
6: Domka K, Goral A, Firczuk M. cROSsing the Line: Between Beneficial and
Harmful Effects of Reactive Oxygen Species in B-Cell Malignancies. Front
Immunol. 2020 Jul 21;11:1538. doi: 10.3389/fimmu.2020.01538. PMID: 32793211;
PMCID: PMC7385186.
7: Bobrowicz M, Slusarczyk A, Domagala J, Dwojak M, Ignatova D, Chang YT, Iselin
C, Miazek-Zapala N, Marhelava K, Guenova E, Winiarska M. Selective inhibition of
HDAC6 sensitizes cutaneous T-cell lymphoma to PI3K inhibitors. Oncol Lett. 2020
Jul;20(1):533-540. doi: 10.3892/ol.2020.11587. Epub 2020 May 6. PMID: 32565979;
PMCID: PMC7285804.
8: Bajor M, Graczyk-Jarzynka A, Marhelava K, Kurkowiak M, Rahman A, Aura C,
Russell N, Zych AO, Firczuk M, Winiarska M, Gallagher WM, Zagozdzon R. Triple
Combination of Ascorbate, Menadione and the Inhibition of Peroxiredoxin-1
Produces Synergistic Cytotoxic Effects in Triple-Negative Breast Cancer Cells.
Antioxidants (Basel). 2020 Apr 16;9(4):320. doi: 10.3390/antiox9040320. PMID:
32316111; PMCID: PMC7222372.
9: Białopiotrowicz E, Noyszewska-Kania M, Kachamakova-Trojanowska N, Łoboda A,
Cybulska M, Grochowska A, Kopczyński M, Mikula M, Prochorec-Sobieszek M, Firczuk
M, Graczyk-Jarzynka A, Zagożdżon R, Ząbek A, Młynarz P, Dulak J, Górniak P,
Szydłowski M, Pyziak K, Martyka J, Sroka-Porada A, Jabłońska E, Polak A,
Kowalczyk P, Szumera-Ciećkiewicz A, Chapuy B, Rzymski T, Brzózka K, Juszczyński
P. Serine Biosynthesis Pathway Supports MYC-miR-494-EZH2 Feed-Forward Circuit
Necessary to Maintain Metabolic and Epigenetic Reprogramming of Burkitt Lymphoma
Cells. Cancers (Basel). 2020 Mar 3;12(3):580. doi: 10.3390/cancers12030580.
PMID: 32138178; PMCID: PMC7139810.
10: Firczuk M, Bajor M, Graczyk-Jarzynka A, Fidyt K, Goral A, Zagozdzon R.
Harnessing altered oxidative metabolism in cancer by augmented prooxidant
therapy. Cancer Lett. 2020 Feb 28;471:1-11. doi: 10.1016/j.canlet.2019.11.037.
Epub 2019 Dec 4. PMID: 31811907.
11: Bobrowicz M, Zagozdzon R, Domagala J, Vasconcelos-Berg R, Guenova E,
Winiarska M. Monoclonal Antibodies in Dermatooncology-State of the Art and
Future Perspectives. Cancers (Basel). 2019 Sep 24;11(10):1420. doi:
10.3390/cancers11101420. PMID: 31554169; PMCID: PMC6826541.
12: Sasi BK, Martines C, Xerxa E, Porro F, Kalkan H, Fazio R, Turkalj S, Bojnik
E, Pyrzynska B, Stachura J, Zerrouqi A, Bobrowicz M, Winiarska M, Priebe V,
Bertoni F, Mansouri L, Rosenquist R, Efremov DG. Inhibition of SYK or BTK
augments venetoclax sensitivity in SHP1-negative/BCL-2-positive diffuse large
B-cell lymphoma. Leukemia. 2019 Oct;33(10):2416-2428. doi:
10.1038/s41375-019-0442-8. Epub 2019 Mar 14. PMID: 30872780.
13: Fidyt K, Pastorczak A, Goral A, Szczygiel K, Fendler W, Muchowicz A,
Bartlomiejczyk MA, Madzio J, Cyran J, Graczyk-Jarzynka A, Jansen E, Patkowska E,
Lech-Maranda E, Pal D, Blair H, Burdzinska A, Pedzisz P, Glodkowska-Mrowka E,
Demkow U, Gawle-Krawczyk K, Matysiak M, Winiarska M, Juszczynski P, Mlynarski W,
Heidenreich O, Golab J, Firczuk M. Targeting the thioredoxin system as a novel
strategy against B-cell acute lymphoblastic leukemia. Mol Oncol. 2019
May;13(5):1180-1195. doi: 10.1002/1878-0261.12476. Epub 2019 Apr 5. PMID:
30861284; PMCID: PMC6487705.
14: Wolosz D, Walczak A, Szparecki G, Dwojak M, Winiarska M, Wolinska E,
Gornicka B. Deleted in Liver Cancer 2 (DLC2) protein expression in
hepatocellular carcinoma. Eur J Histochem. 2019 Feb 18;63(1):2981. doi:
10.4081/ejh.2019.2981. PMID: 30827083; PMCID: PMC6383041.
15: Graczyk-Jarzynka A, Goral A, Muchowicz A, Zagozdzon R, Winiarska M, Bajor M,
Trzeciecka A, Fidyt K, Krupka JA, Cyran J, Szczygiel K, Efremov DG, Gobessi S,
Jagielski A, Siudakowska K, Bobrowicz M, Klopotowska M, Barankiewicz J, Malenda
A, Lech-Maranda E, Miazek-Zapala N, Skarzynski PH, Domagala A, Golab J, Firczuk
M. Inhibition of thioredoxin-dependent H<sub>2</sub>O<sub>2</sub> removal
sensitizes malignant B-cells to pharmacological ascorbate. Redox Biol. 2019
Feb;21:101062. doi: 10.1016/j.redox.2018.11.020. Epub 2018 Nov 29. PMID:
30576925; PMCID: PMC6302138.
16: Domagala A, Fidyt K, Bobrowicz M, Stachura J, Szczygiel K, Firczuk M.
Typical and Atypical Inducers of Lysosomal Cell Death: A Promising Anticancer
Strategy. Int J Mol Sci. 2018 Aug 1;19(8):2256. doi: 10.3390/ijms19082256. PMID:
30071644; PMCID: PMC6121368.
17: Chlebowska-Tuz J, Sokolowska O, Gaj P, Lazniewski M, Firczuk M, Borowiec K,
Sas-Nowosielska H, Bajor M, Malinowska A, Muchowicz A, Ramji K, Stawinski P,
Sobczak M, Pilch Z, Rodziewicz-Lurzynska A, Zajac M, Giannopoulos K, Juszczynski
P, Basak GW, Plewczynski D, Ploski R, Golab J, Nowis D. Inhibition of protein
disulfide isomerase induces differentiation of acute myeloid leukemia cells.
Haematologica. 2018 Nov;103(11):1843-1852. doi: 10.3324/haematol.2018.190231.
Epub 2018 Jul 12. PMID: 30002127; PMCID: PMC6278960.
18: Pyrzynska B, Dwojak M, Zerrouqi A, Morlino G, Zapala P, Miazek N, Zagozdzon
A, Bojarczuk K, Bobrowicz M, Siernicka M, Machnicki MM, Gobessi S, Barankiewicz
J, Lech-Maranda E, Efremov DG, Juszczynski P, Calado D, Golab J, Winiarska M.
FOXO1 promotes resistance of non-Hodgkin lymphomas to anti-CD20-based therapy.
Oncoimmunology. 2018 Jan 25;7(5):e1423183. doi: 10.1080/2162402X.2017.1423183.
PMID: 29721381; PMCID: PMC5927521.
19: Domagala A, Stachura J, Gabrysiak M, Muchowicz A, Zagozdzon R, Golab J,
Firczuk M. Inhibition of autophagy sensitizes cancer cells to Photofrin-based
photodynamic therapy. BMC Cancer. 2018 Feb 20;18(1):210. doi:
10.1186/s12885-018-4126-y. PMID: 29463237; PMCID: PMC5819678.
20: Oei VYS, Siernicka M, Graczyk-Jarzynka A, Hoel HJ, Yang W, Palacios D,
Almåsbak H, Bajor M, Clement D, Brandt L, Önfelt B, Goodridge J, Winiarska M,
Zagozdzon R, Olweus J, Kyte JA, Malmberg KJ. Intrinsic Functional Potential of
NK-Cell Subsets Constrains Retargeting Driven by Chimeric Antigen Receptors.
Cancer Immunol Res. 2018 Apr;6(4):467-480. doi: 10.1158/2326-6066.CIR-17-0207.
Epub 2018 Feb 19. PMID: 29459477.
21: Bajor M, Zych AO, Graczyk-Jarzynka A, Muchowicz A, Firczuk M, Trzeciak L, Gaj
P, Domagala A, Siernicka M, Zagozdzon A, Siedlecki P, Kniotek M, O'Leary PC,
Golab J, Zagozdzon R. Targeting peroxiredoxin 1 impairs growth of breast cancer
cells and potently sensitises these cells to prooxidant agents. Br J Cancer.
2018 Oct;119(7):873-884. doi: 10.1038/s41416-018-0263-y. Epub 2018 Oct 5. PMID:
30287919; PMCID: PMC6189216.
22: Bobrowicz M, Dwojak M, Pyrzynska B, Stachura J, Muchowicz A, Berthel E,
Dalla-Venezia N, Kozikowski M, Siernicka M, Miazek N, Zapala P, Domagala A,
Bojarczuk K, Malenda A, Barankiewicz J, Graczyk-Jarzynka A, Zagozdzon A,
Gabrysiak M, Diaz JJ, Karp M, Lech-Maranda E, Firczuk M, Giannopoulos K, Efremov
DG, Laurenti L, Baatout D, Frenzel L, Malinowska A, Slabicki M, Zenz T, Zerrouqi
A, Golab J, Winiarska M. HDAC6 inhibition upregulates CD20 levels and increases
the efficacy of anti-CD20 monoclonal antibodies. Blood. 2017 Oct
5;130(14):1628-1638. doi: 10.1182/blood-2016-08-736066. Epub 2017 Aug 22. PMID:
28830887.
23: Winiarska M, Nowis D, Firczuk M, Zagozdzon A, Gabrysiak M, Sadowski R,
Barankiewicz J, Dwojak M, Golab J. Selection of an optimal promoter for gene
transfer in normal B cells. Mol Med Rep. 2017 Sep;16(3):3041-3048. doi:
10.3892/mmr.2017.6974. Epub 2017 Jul 14. PMID: 28713922; PMCID: PMC5548056.
24: Lechowicz U, Gambin T, Pollak A, Podgorska A, Stawinski P, Franke A,
Petersen BS, Firczuk M, Oldak M, Skarzynski H, Ploski R. Iterative Sequencing
and Variant Screening (ISVS) as a novel pathogenic mutations search strategy -
application for TMPRSS3 mutations screen. Sci Rep. 2017 May 31;7(1):2543. doi:
10.1038/s41598-017-02315-w. PMID: 28566687; PMCID: PMC5451398.
25: Graczyk-Jarzynka A, Zagozdzon R, Muchowicz A, Siernicka M, Juszczynski P,
Firczuk M. New insights into redox homeostasis as a therapeutic target in B-cell
malignancies. Curr Opin Hematol. 2017 Jul;24(4):393-401. doi:
10.1097/MOH.0000000000000351. PMID: 28402987; PMCID: PMC5470855.
26: Wasilewska A, Winiarska M, Olszewska M, Rudnicka L. Interleukin-17
inhibitors. A new era in treatment of psoriasis and other skin diseases. Postepy
Dermatol Alergol. 2016 Aug;33(4):247-52. doi: 10.5114/ada.2016.61599. Epub 2016
Aug 16. PMID: 27605893; PMCID: PMC5004212.
27: Słabicki M, Lee KS, Jethwa A, Sellner L, Sacco F, Walther T, Hüllein J,
Dietrich S, Wu B, Lipka DB, Oakes CC, Mamidi S, Pyrzyńska B, Winiarska M, Oleś
M, Seifert M, Plass C, Kirschfink M, Boettcher M, Gołąb J, Huber W, Fröhling S,
Zenz T. Dissection of CD20 regulation in lymphoma using RNAi. Leukemia. 2016
Dec;30(12):2409-2412. doi: 10.1038/leu.2016.230. Epub 2016 Aug 18. PMID:
27560109.
28: Gabrysiak M, Wachowska M, Barankiewicz J, Pilch Z, Ratajska A, Skrzypek E,
Winiarska M, Domagala A, Rygiel TP, Jozkowicz A, Boon L, Golab J, Firczuk M. Low
dose of GRP78-targeting subtilase cytotoxin improves the efficacy of
photodynamic therapy in vivo. Oncol Rep. 2016 Jun;35(6):3151-8. doi:
10.3892/or.2016.4723. Epub 2016 Apr 1. PMID: 27035643; PMCID: PMC4872279.